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32)/b24-11-/t12-
extracted from patent WO 2013059666A1
Kushenol A (25 μM) exhibits a highly potent inhibitory activity on ABTS+ radical scavenging with an IC50 value of 9
46)47)40(53-43)66-32-7-2-4-24-9-12-31(55)36(24)32)38(58)48-15-17-64-19-21-65-20-18-63-16-14-35(57)50-29-6-3-5-26-37(29)42(61)54(41(26)60)30-11-13-34(56)52-39(30)59/h2-8
but not des-Arg9-bradykinin (effects mediated by the bradykinin B1 receptors)
EUK 134 bridin 32)/b24-11-/t12-EUK 134, a synthetic superoxide dismutase (SOD) catalase mimetic, has exhibited potent antioxidant activities and inhibited the formation of amyloid and related amyloid fibril. In vitro: EUK 134, a salen manganese complex, showed potent catalase and cytoprotective activities and SOD activity. After middle cerebral artery occlusion, EUK 134 administration at 3 hr significantly reduced brain infarct size, with the highest dose apparently preventing
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