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Thalidomide-O-amido-C8-NH2 is a degron-linker (refer to Compound DL7-TL)
a natural compound isolated from the bark of the lapacho tree
E6130 also shows agonistic activity via CX3CR1 with respect to GTPγS binding (EC50 = 133 nM) and β-arrestin recruitment (EC50 = 2
but not monoamine oxidase proteins MAO-A and MAO-B (>5 µM)
PROTAC ERRα Degrader-3 is inactive against ERRβ and ERRγ proteins
STF-31 5208 Thalidomide-O-amido-C8-NH2 is a degron-linker (referSTF 31 is a selective inhibitor of glucose transporter 1 (GLUT1), with an IC50 of 1M. Product information CAS Number: 724741 75 7 Molecular Weight: 423. 53 Formula: C23H25N3O3S Chemical Name: 4 [(4 tert butylbenzenesulfonamido)methyl] N (pyridin 3 yl)benzamide Smiles: CC(C)(C)C1C=CC(=CC=1)S(=O)(=O)NCC1C=CC(=CC=1)C(=O)NC1C=NC=CC=1 InChiKey: NGQPRVWTFNBUHA UHFFFAOYSA N InChi: InChI=1S C23H25N3O3S c1 23(2,3)19 10 12 21(13 11 19)30(28,29)25 15 17 6 8 18(9