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They are therefore also less common to find, even more so on 1st edition stamps of other sets (like the Gym and Neo series) than on the Base Set Holos

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Isochron ScepterIsochron Scepter can do a few different things for this strategy

With lots of looting going on, Emet-Selch can easily employ discard payoffs like Monument to Endurance and Oskar, Rubbish Reclaimer, turning Emet-Selch into strict card advantage

You do need to play him in a very synergistic deck to abuse his abilities, so the natural home is alongside creatures with the Undying ability