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AML and DLBCL cell lines in a dose- and time-dependent manner
InChi: InChI=1S/C28H29BrN4O3
InChiKey: SPYIETQLOVDJCF-WQLSENKSSA-N
Regulated necrosis and its implications in toxicology
respectively) and anti-IgM /anti-CD40 co-stimulated B cell proliferation (EC50=108±55 nM)
Ailanthone Size:Contact [email protected] for quotation AML and DLBCL cell linesAilanthone (AIL, 13 Dehydrochaparrinone), a natural anti hepatocellular carcinoma (HCC) component in Ailanthus altissima, induces G0 G1 phase cell cycle arrest by decreasing expression of cyclins and CDKs and increases expression of p21 and p27. Ailanthone triggers DNA damage characterized by activation of the ATM ATR pathway. Ailanthone induces apoptosis which is mitochondrion mediated and involves the PI3K AKT signaling pathway in Huh7 cells.
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