LT175 Catalog No.:M22494-C Smiles: NC1N[C@]23[C@H]([C@H]4O[C@](O)(O[C@@H](C2O)[C@]4(O)CO)[C@H]3O)[C@@H](O)N=1

Smiles: NC1N[C@]23[C@H]([C@H]4O[C@](O)(O[C@@H](C2O)[C@]4(O)CO)[C@H]3O)[C@@H](O)N=1

Formula: C22H44O2

3-thiazolidin-2-imine

InChiKey: FMOQHLZNJFXULZ-UHFFFAOYSA-N

CAS Number: 87-66-1

LT175 Catalog No.:M22494-C Smiles: NC1N[C@]23[C@H]([C@H]4O[C@](O)(O[C@@H](C2O)[C@]4(O)CO)[C@H]3O)[C@@H](O)N=1LT175 is a dual PPAR ligand. Peroxisome proliferator activated receptors (PPARs) are ligand dependent transcription factors regulating lipid and glucose metabolism. In vitro: LT175 was identified as a partial agonist against PPAR and interacted with a newly identified region of the PPAR ligand binding domain. LT175 could differentially activate PPAR target genes involved in fatty acid esterification and storage, resulting in a less severe lipid