YKL-06-061 roxyandrostenedione Smiles: O=C(C1C=CC(Cl)=CC=1)N(CC1C=CC=CC=1)C1CCCCC1

Smiles: O=C(C1C=CC(Cl)=CC=1)N(CC1C=CC=CC=1)C1CCCCC1

Chemical Name: 3-{5-[(2

34 and 105 nM for c-Raf1

with 70-90% growth inhibition at 10 microM

suppresses steatohepatitis and tumorigenesis by activating autophagy in mice fed an atherogenic high-fat diet

YKL-06-061 roxyandrostenedione Smiles: O=C(C1C=CC(Cl)=CC=1)N(CC1C=CC=CC=1)C1CCCCC1YKL 06 061 is a potent, selective, second generation salt inducible kinase (SIK) inhibitor with IC50 values of 6. 56 nM 1. 77 nM 20. 5 nM for SIK1 2 3, respectively. Product information CAS Number: 2172617 15 9 Molecular Weight: 527. 66 Formula: C30H37N7O2 Chemical Name: 1 cyclobutyl 3 (2,6 dimethylphenyl) 7 {[2 methoxy 4 (4 methylpiperazin 1 yl)phenyl]amino} 1H,2H,3H,4H pyrimido[4,5 d][1,3]diazin 2 one Smiles: