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Formula: C17H15Cl2N3O2S2
is a highly potent and selective hypoxia-activated pro-drug targeting hypoxic regions of solid tumors with an IC50 of 19 nM
Activating ALK mutations found in neuroblastoma are inhibited by Crizotinib and NVP-TAE684
) leads to significant tumor growth inhibition in female nude mice bearing LoVo tumors
JIB-04 (NSC693627
L-779450 Catalog No.:M8298-10 Formula: C17H15Cl2N3O2S2L 779450 is a potent, selective and ATP competitive Raf kinase inhibitor (IC50 = 10 nM). L 779450 suppresses DNA synthesis and induces apoptosis in cells that proliferate in response to Raf 1 and A Raf but not B Raf. Product information CAS Number: 303727 31 3 Molecular Weight: 347. 80 Formula: C20H14ClN3O Chemical Name: 2 chloro 5 [2 phenyl 5 (pyridin 4 yl) 1H imidazol 4 yl]phenol Smiles: OC1=CC(=CC=C1Cl)C1N=C(NC=1C1C=CN=CC=1)C1C=CC=CC=1 InChiKey:
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