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Cassiaside B
Smiles: NC(C1=CC(O)=C(C=C1)C(O)=O)C(O)=O
Solubility: DMSO : 50 mg/mL (324
Smiles: COC1C2=C3[C@@H](CC4=CC=CC=C42)NCCC3=CC=1OC
has high affinity for recombinant A1 and A3 receptors
trans-AUCB opurvalanol A Cassiaside BIC50: 0. 5 nM trans AUCB is a potent inhibitor of soluble epoxide hydrolase (sEH). Soluble epoxide hydrolase (sEH) can convert epoxides to their corresponding diols. Inhibitors of sEH have anti hypertensive, anti inflammatory, neuroprotective, and cardioprotective effects. In vitro: A previous study showed that the pretreatment with DAPT could substantially potentiate the growth inhibition caused by t AUCB in U251 and U87 cells. Moreover, the
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