There are restrictions on the S materials, but with the "Graydle" Deck, you can use the effect of "Graydle Slime Jr.", and with the "Fish" Deck, you can combine Royal Swamp Eel, Double Fin Shark, and Silent Angler, so I don't think there's a problem
For instance, Patchwork Beastie will be able to attack, Impossible Inferno will exile cards off the top of your library, and Scuttletide will give Crabs you control +1/+1
Simply put, the deathtouch ability means that any amount of damage that card deals to another creature is enough to kill it no matter what the other creatures toughness is
then, it can get set up early while not necessarily needing an optimal hand
As WackaFrog put it: I think people are underestimating how easy it is to get the draw effect