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11-pentaen-3-yl}ethyl)-N-{2-[2-(2-{[2-(2
as well as PARP cleavage
Na/c1-27-15-10-19(29-3)16(20(11-15)30-4)7-8-31(25
Voronkov A
9(10):630-5
Saxagliptin hydrate esceinamine Isomer II 11-pentaen-3-yl}ethyl)-N-{2-[2-(2-{[2-(2Saxagliptin, also known as BMS 477118, is a new oral hypoglycemic (anti diabetic drug) of the new dipeptidyl peptidase 4 (DPP 4) inhibitor class of drugs. Saxagliptin was approved in 2008 for the treatment of type 2 diabetes. Saxagliptin is a competitive DPP4 inhibitor that slows the inactivation of the incretin hormones, thereby increasing their bloodstream concentrations and reducing fasting and postprandial glucose concentrations in a glucose
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