(R)-FT671 e-1 3-dione for the treatment of moderate

for the treatment of moderate to severe osteoarthritis of the knee: results of a 24-week

CAS Number: 79183-19-0

cellular levels of active β-catenin were reduced concomitant with an increase in the expression of E-cadherin

It is structurally very similar to resiquimod differing only by an oxygen for nitrogen switch

The genotype coverage of PSI-7977 by using GT 1b (Con1)-

(R)-FT671 e-1 3-dione for the treatment of moderate(R) FT671 is the R isomer of FT671. FT671 is a potent, non covalent and selective USP7 inhibitor with an IC50 of 52 nM and binds to the USP7 catalytic domain with a Kd of 65 nM. Product information CAS Number: 1959551 27 9 Molecular Weight: 533. 48 Formula: C24H23F4N7O3 Chemical Name: 5 ({1 [(3R) 4,4 difluoro 3 (3 fluoro 1H pyrazol 1 yl)butanoyl] 4 hydroxypiperidin 4 yl}methyl) 1 (4 fluorophenyl) 1H,4H,5H pyrazolo[3,4 d]pyrimidin 4 one Smiles: