As it enters, choose a card type shared among two exiled cards used to craft it
Outside of exactly the card Deafening Clarion, Disdainful Stroke can answer all the problematic cards that Negate can, but Disdainful Stroke has the added benefit of tagging Lyra Dawnbringer and Ravenous Chupacabra
Plus, it's a significant enough threat on its own for 4 mana
Kaito, Cunning Infiltrator has a few things going on for it, notably that you can give a creature unblockable and profit from your creatures hitting your opponents
Fred and Daphne team up to lead the charge through your deck or over your opponents creatures (which is an analogy well use for solving the mystery of your Commander pod), while Velma is apt at cracking Clues and acts as sort of a Clue, herself, once given enough resources