Well, check out the Collecting Secrets of Strixhaven article for more details on what you can pull, but in short: There are 65 Mystical Archive cards in Secrets of Strixhaven , consisting of 25 uncommon, 25 rare, and 15 mythic rare cards
Then she can -4 once after arrival with her initial loyalty to Barter in Blood the table for two sacrifices each, which will be two cards drawn with her static ability
However, this only applies if you're using the Stellar Crown Duraludon
Most of the best villain team cards exceed this $300 plateau, but few can separate themselves from the pack forming around the benchmark
The card pool decision comes down to two questions: how many Life cards do you want to remove proactively, and how deep does your Blue counter package need to be