In the context of The Brothers War, the new keyword is excellent at providing you a way to make use of Powerstones while not punishing you for leaving all your rocks in the car before battle, which means a wide variety of Commander decks will likely be seeking to include Prototype cards in their lists
I cant say, but playtesting certainly wouldnt hurt
Cards like Timetwister, Bazaar of Baghdad, The Tabernacle At Pendrell Vale, and Mishra's Workshop all come to mind
Black is where we fall off a bit, but it still is a good card, though one I wouldnt have on this list otherwise: Phyrexian Tower
They also include five spindown life counters, tokens for each of the decks, and punchout +1/+1 counters